Abstract :The emergence of newer and novel methods of chemical synthesis has provided a new dimension to the existing scenario of pharmacy and medicine. Exploration of new materials with multifunctional properties and performance of small and macro sizes has opened up a new world of research where chemical, pharmaceutical and material sciences have overlapped significantly to design tailor made entities of pharmacological and pharmaceutical importance. In spite of ever seen large number of publications, monographs and patents in medicine and pharmacy, still there are some avenues that need a rigorous innovation and investigations for doing something much better to mankind. In recent times two areas of research have stimulated chemists and pharmacists worldwide, one is responsive drug delivery and the second one is targeted drug delivery. Whereas the former one pertains to the phenomenon of producing a desired and larger change in drug delivery process, the later one is aimed at triggering the drug to a desired target only without disturbing the normal life-style of the patients. Although a long journey of pharmaceutical research has been made in recent decades in the areas of drug delivery systems and technology, yet designing a drug that could respond and target with extreme precision is still a dream.